Publications

2018

• Principal-Agent Problem with Common Agency without Communication
  
  • Mastrolia Thibaut
  • Ren Zhenjie
  , 2018. In this paper, we consider a problem of contract theory in which several Principals hire a common Agent and we study the model in the continuous time setting. We show that optimal contracts should satisfy some equilibrium conditions and we reduce the optimisation problem of the Principals to a system of coupled Hamilton-Jacobi-Bellman (HJB) equations. We provide conditions ensuring that for risk-neutral Principals, the system of coupled HJB equations admits a solution. Further, we apply our study in a more specific linear-quadratic model where two interacting Principals hire one common Agent. In this continuous time model, we extend the result of Bernheim and Whinston (1986) in which the authors compare the optimal effort of the Agent in a non-cooperative Principals model and that in the aggregate model, by showing that these two optimisations coincide only in the first best case. We also study the sensibility of the optimal effort and the optimal remunerations with respect to appetence parameters and the correlation between the projects. (10.1137/17M1133609)
  DOI : 10.1137/17M1133609
• Development and performance of npde for the evaluation of time-to-event models
  
  • Cerou Marc
  • Lavielle Marc
  • Brendel Karl
  • Chenel Marylore
  • Comets Emmanuelle
  Pharmaceutical Research, American Association of Pharmaceutical Scientists, 2018, 35 (2), pp.30. Purpose - Normalised prediction distribution errors (npde) are used to graphically and statistically evaluate mixed-effect models for continuous responses. In this study, our aim was to extend npde to time-to-event (TTE) models and evaluate their performance. Methods - Let V denote a dataset with censored TTE observations. The null hypothesis (H) is that observations in V can be described by model M. We extended npde to TTE models using imputations to take into account censoring. We then evaluated their performance in terms of type I error and power to detect model misspecifications for TTE data by means of a simulation study with different sample sizes. Results - Type I error was found to be close to the expected 5% significance level for all sample sizes tested. The npde were able to detect misspecifications in the baseline hazard as well as in the link between the longitudinal variable and the survival function. The ability to detect model misspecifications increased as the difference in the shape of the survival function became more apparent. As expected, the power also increased as the sample size increased. Imputing the censored events tended to decrease the percentage of rejections. Conclusions - We have shown that npde can be readily extended to TTE data and that they perform well with an adequate type I error. (10.1007/s11095-017-2291-3)
  DOI : 10.1007/s11095-017-2291-3
• Quantitative estimates for the flux of TASEP with dilute site disorder
  
  • Bahadoran Christophe
  • Bodineau Thierry
  Electronic Journal of Probability, Institute of Mathematical Statistics (IMS), 2018, 23. We prove that the flux function of the totally asymmetric simple exclusion process (TASEP) with site disorder exhibits a flat segment for sufficiently dilute disorder. For high dilution, we obtain an accurate description of the flux. The result is established under a decay assumption of the maximum current in finite boxes, which is implied in particular by a sufficiently slow power tail assumption on the disorder distribution near its minimum. To circumvent the absence of explicit invariant measures, we use an original renormalization procedure and some ideas inspired by homogenization. (10.1214/18-EJP137)
  DOI : 10.1214/18-EJP137
• The Quasispecies for the Wright–Fisher Model
  
  • Cerf Raphaël
  • Dalmau Joseba
  Evolutionary Biology, Springer, 2018, 45 (3), pp.318-323. We consider the classical Wright-Fisher model of population genetics. We prove the existence of an error threshold for the mutation probability per nucleotide, below which a quasispecies is formed. We show a new phenomenon, specific to a finite population model, namely the existence of a population threshold: to ensure the stability of the quasispecies, the population size has to be at least of the same order as the genome length. We derive an explicit formula describing the quasispecies. (10.1007/s11692-018-9452-0)
  DOI : 10.1007/s11692-018-9452-0
• Impact of subsampling and tree depth on random forests
  
  • Duroux Roxane
  • Scornet Erwan
  ESAIM: Probability and Statistics, EDP Sciences, 2018, 22, pp.96-128. Random forests are ensemble learning methods introduced by Breiman [Mach. Learn. 45 (2001) 5–32] that operate by averaging several decision trees built on a randomly selected subspace of the data set. Despite their widespread use in practice, the respective roles of the different mechanisms at work in Breiman’s forests are not yet fully understood, neither is the tuning of the corresponding parameters. In this paper, we study the influence of two parameters, namely the subsampling rate and the tree depth, on Breiman’s forests performance. More precisely, we prove that quantile forests (a specific type of random forests) based on subsampling and quantile forests whose tree construction is terminated early have similar performances, as long as their respective parameters (subsampling rate and tree depth) are well chosen. Moreover, experiments show that a proper tuning of these parameters leads in most cases to an improvement of Breiman’s original forests in terms of mean squared error. (10.1051/ps/2018008)
  DOI : 10.1051/ps/2018008
• Commentaires sur le projet de document consensus de l’OCDE sur les considérations environnementales relatives à l’évaluation des risques associé. Paris, le 23 mai 2018
  
  • Comité Scientifique Du Haut Conseil Des Biotechnologies .
  • Angevin Frédérique
  • Bagnis Claude
  • Bar-Hen Avner
  • Barny Marie Anne M. A.
  • Bellivier Florence
  • Berny Philippe
  • Boireau Pascal
  • Brévault Thierry
  • Chauvel Bruno B.
  • Coléno François
  • Couvet Denis
  • Dassa Elie
  • Eychenne Nathalie
  • Franche Claudine
  • Guerche Philippe
  • Guillemain Joël
  • Hernandez Raquet Guillermina
  • Jestin André
  • Klonjkowski Bernard
  • Lavielle Marc
  • Le Corre Valérie V.
  • Lemaire Olivier O.
  • Lereclus Didier
  • Maximilien Rémi
  • Meurs Eliane
  • Moreau de Bellaing Cédric
  • Naffakh Nadia
  • Négre Didier
  • Noyer Jean-Louis
  • Ochatt Sergio
  • Pages Jean-Christophe
  • Parzy Daniel
  • Regnault-Roger Catherine
  • Renard Michel
  • Saindrenan Patrick
  • Simonet Pascal
  • Troadec Marie-Bérengère
  • Vaissière Bernard
  • de Verneuil Hubert
  • Vilotte Jean-Luc
  , 2018, pp.25 p.. Le Haut Conseil des biotechnologies (HCB) a été sollicité le 4 avril 2018 par la direction générale de l’alimentation du ministère de l’Agriculture et de l’Alimentation et par la direction générale de la prévention des risques du ministère de la Transition écologique et solidaire pour examiner et commenter le projet de document consensus de l’OCDE (version du 3 avril 2018) sur les considérations environnementales relatives à l’évaluation des risques associés à la dissémination de plantes génétiquement modifiées en vue de la réunion du groupe de travail de l’OCDE sur l’harmonisation de la surveillance réglementaire en biotechnologie les 21 et 22 juin 2018. Le Comité scientifique (CS)1 du HCB a examiné ce document en séance du 26 avril 2018 sous la présidence de Jean-Christophe Pagès. Les commentaires du CS du HCB à destination de l’OCDE, en version française et anglaise2, ont été validés par voie électronique et transmis aux autorités compétentes françaises le 23 mai 2018, et publiés après envoi à l’OCDE le 30 mai 2018.
• From Hammersley's lines to Hammersley's trees
  
  • Basdevant Anne-Laure
  • Gerin Lucas
  • Gouere Jean-Baptiste
  • Singh Arvind
  Probability Theory and Related Fields, Springer Verlag, 2018, 171 (1-2), pp.1-51. We construct a stationary random tree, embedded in the upper half plane, with prescribed offspring distribution and whose vertices are the atoms of a unit Poisson point process. This process which we call Hammersley's tree process extends the usual Hammersley's line process. Just as Hammersley's process is related to the problem of the longest increasing subsequence, this model also has a combinatorial interpretation: it counts the number of heaps (i.e. increasing trees) required to store a random permutation. This problem was initially considered by Byers et. al (2011) and Istrate and Bonchis (2015) in the case of regular trees. We show, in particular, that the number of heaps grows logarithmically with the size of the permutation. (10.1007/s00440-017-0772-2)
  DOI : 10.1007/s00440-017-0772-2
• Vertices with fixed outdegrees in large Galton-Watson trees
  
  • Thévenin Paul
  Electronic Journal of Probability, Institute of Mathematical Statistics (IMS), 2018, 25 (none). We are interested in nodes with fixed outdegrees in large conditioned Galton--Watson trees. We first study the scaling limits of processes coding the evolution of the number of such nodes in different explorations of the tree (lexicographical order and contour order) starting from the root. We give necessary and sufficient conditions for the limiting processes to be centered, thus measuring the linearity defect of the evolution of the number of nodes with fixed outdegrees. This extends results by Labarbe & Marckert in the case of the contour-ordered counting process of leaves in uniform plane trees. Then, we extend results obtained by Janson concerning the asymptotic normality of the number of nodes with fixed outdegrees. (10.1214/20-EJP465)
  DOI : 10.1214/20-EJP465
• Sensing Von Economo Neurons in the Insula with Multi-shell Diffusion MRI
  
  • Wassermann Demian
  • Nguyen Dang Van
  • Gallardo Guillermo
  • Li Jing-Rebecca
  • Cai Weidong
  • Menon Vinod
  , 2018.
• Markov chains
  
  • Douc Randal
  • Moulines Eric
  • Priouret Pierre
  • Soulier Philippe
  , 2018, pp.757. This book covers the classical theory of Markov chains on general state-spaces as well as many recent developments. The theoretical results are illustrated by simple examples, many of which are taken from Markov Chain Monte Carlo methods. The book is self-contained, while all the results are carefully and concisely proven. Bibliographical notes are added at the end of each chapter to provide an overview of the literature (10.1007/978-3-319-97704-1)
  DOI : 10.1007/978-3-319-97704-1
• Darboux–Moutard transformations and Poincare–Steklov operators
  
  • Novikov Roman
  • Taimanov Iskander
  Proceedings of the Steklov Institute of Mathematics, MAIK Nauka/Interperiodica, 2018, 302, pp.315–324. Formulas relating Poincare–Steklov operators for Schrödinger equations related by Darboux–Moutard transformations are derived. They can be used for testing algorithms of reconstruction of the potential from measurements at the boundary. (10.1134/S0081543818060160)
  DOI : 10.1134/S0081543818060160
• FEM and BEM simulations with the Gypsilab framework
  
  • Alouges François
  • Aussal Matthieu
  SMAI Journal of Computational Mathematics, Société de Mathématiques Appliquées et Industrielles (SMAI), 2018, 4, pp.297-318. (10.5802/smai-jcm.36)
  DOI : 10.5802/smai-jcm.36
• Fluctuations and Temperature Effects in Bose-Einstein Condensation
  
  • de Bouard Anne
  • Debussche Arnaud
  • Fukuizumi Reika
  • Poncet Romain
  ESAIM: Proceedings and Surveys, EDP Sciences, 2018, 61, pp.55-67. The modeling of cold atoms systems has known an increasing interest in the theoretical physics community, after the first experimental realizations of Bose Einstein condensates, some twenty years ago. We here review some analytical and numerical results concerning the influence of fluctuations , either arising from fluctuations of the confining parameters, or due to temperature effects, in the models describing the dynamics of such condensates. (10.1051/proc/201861055)
  DOI : 10.1051/proc/201861055
• Random planar maps and growth-fragmentations
  
  • Bertoin Jean
  • Curien Nicolas
  • Kortchemski Igor
  The Annals of Probability, Institute of Mathematical Statistics, 2018, 46 (1), pp.207-260. (10.1214/17-AOP1183)
  DOI : 10.1214/17-AOP1183
• Optimizing supports for additive manufacturing
  
  • Allaire Grégoire
  • Bogosel Beniamin
  Structural and Multidisciplinary Optimization, Springer Verlag, 2018, 58 (6), pp.2493-2515. In additive manufacturing process support structures are often required to ensure the quality of the final built part. In this article we present mathematical models and their numerical implementations in an optimization loop, which allow us to design optimal support structures. Our models are derived with the requirement that they should be as simple as possible, computationally cheap and yet based on a realistic physical modeling. Supports are optimized with respect to two different physical properties. First, they must support overhanging regions of the structure for improving the stiffness of the supported structure during the building process. Second, supports can help in channeling the heat flux produced by the source term (typically a laser beam) and thus improving the cooling down of the structure during the fabrication process. Of course, more involved constraints or manufacturability conditions could be taken into account, most notably removal of supports. Our work is just a first step, proposing a general framework for support optimization. Our optimization algorithm is based on the level set method and on the computation of shape derivatives by the Hadamard method. In a first approach, only the shape and topology of the supports are optimized, for a given and fixed structure. In second and more elaborated strategy, both the supports and the structure are optimized, which amounts to a specific multiphase optimization problem. Numerical examples are given in 2-d and 3-d.
• An integrate-and-fire model to generate spike trains with long memory
  
  • Richard Alexandre
  • Orio Patricio
  • Tanré Etienne
  Journal of Computational Neuroscience, Springer Verlag, 2018. Long-range dependence (LRD) has been observed in a variety of phenomena in nature, and for several years also in the spiking activity of neurons. Often, this is interpreted as originating from a non-Markovian system. Here we show that a purely Markovian integrate-and-re (IF) model, with a noisy slow adaptation term, can generate data that appears as having LRD with a Hurst exponent (H) greater than 0.5. A proper analysis shows that the asymptotic value of H is 0.5 if a long enough sequence of events is taken into account. For comparison, we also consider a new model of individual IF neuron with fractional noise. The correlations of its spike trains are studied and proved to have long memory, unlike classical IF models. On the other hand, to correctly measure long-range dependence, it is usually necessary to know if the data are stationary. Thus, a methodology to evaluate stationarity of the interspike intervals (ISIs) is presented and applied to the various IF models. In conclusion, the spike trains of our fractional model have the long-range dependence property, while those from classical Markovian models do not. However, Markovian IF models may seem to have it because of apparent non-stationarities. (10.1007/s10827-018-0680-1)
  DOI : 10.1007/s10827-018-0680-1
• Avis en réponse à la saisine HCB - dossier EFSA-GMO-RX009. Paris, le 4 juin 2018
  
  • Comité Scientifique Du Haut Conseil Des Biotechnologies .
  • Angevin Frédérique
  • Bagnis Claude
  • Bar-Hen Avner
  • Barny Marie-Anne
  • Boireau Pascal
  • Brévault Thierry
  • Chauvel Bruno B.
  • Collonnier Cécile
  • Couvet Denis
  • Dassa Elie
  • de Verneuil Hubert
  • Demeneix Barbara
  • Franche Claudine
  • Guerche Philippe
  • Guillemain Joël
  • Hernandez Raquet Guillermina
  • Khalife Jamal
  • Klonjkowski Bernard
  • Lavielle Marc
  • Le Corre Valérie
  • Lefèvre François
  • Lemaire Olivier
  • Lereclus Didier D.
  • Maximilien Rémy
  • Meurs Eliane
  • Naffakh Nadia
  • Négre Didier
  • Noyer Jean-Louis
  • Ochatt Sergio
  • Pages Jean-Christophe
  • Raynaud Xavier
  • Regnault-Roger Catherine
  • Renard Michel M.
  • Renault Tristan
  • Saindrenan Patrick
  • Simonet Pascal
  • Troadec Marie-Bérengère
  • Vaissière Bernard
  • Vilotte Jean-Luc
  , 2018.
• Intrinsic random walks in Riemannian and sub-Riemannian geometry via volume sampling
  
  • Agrachev Andrei
  • Boscain Ugo
  • Neel Robert
  • Rizzi Luca
  ESAIM: Control, Optimisation and Calculus of Variations, EDP Sciences, 2018, 24 (3), pp.1075–1105. We relate some basic constructions of stochastic analysis to differential geometry , via random walk approximations. We consider walks on both Riemannian and sub-Riemannian manifolds in which the steps consist of travel along either geodesics or integral curves associated to orthonormal frames, and we give particular attention to walks where the choice of step is influenced by a volume on the manifold. A primary motivation is to explore how one can pass, in the parabolic scaling limit, from geodesics, orthonormal frames, and/or volumes to diffusions, and hence their infinitesimal generators , on sub-Riemannian manifolds, which is interesting in light of the fact that there is no completely canonical notion of sub-Laplacian on a general sub-Riemannian mani-fold. However, even in the Riemannian case, this random walk approach illuminates the geometric significance of Ito and Stratonovich stochastic differential equations as well as the role played by the volume. (10.1051/cocv/2017037)
  DOI : 10.1051/cocv/2017037
• Infinite Horizon Stochastic Optimal Control Problems with Running Maximum Cost
  
  • Kröner Axel
  • Picarelli Athena
  • Zidani Hasnaa
  SIAM Journal on Control and Optimization, Society for Industrial and Applied Mathematics, 2018, 56 (5), pp.3296-3319. An infinite horizon stochastic optimal control problem with running maximum cost is considered. The value function is characterized as the viscosity solution of a second-order Hamilton-Jacobi-Bellman (HJB) equation with mixed boundary condition. A general numerical scheme is proposed and convergence is established under the assumptions of consistency, monotonicity and stability of the scheme. These properties are verified for a specific semi-Lagrangian scheme. (10.1137/17M115253X)
  DOI : 10.1137/17M115253X
• SEME 2017 : identification de véhicules en utilisant le numéro VIN
  
  • Besson Rémi
  • Etchegaray Christèle
  • Ferrari Luca
  • Nordmann Samuel
  , 2018.
• Log-barrier interior point methods are not strongly polynomial
  
  • Allamigeon Xavier
  • Benchimol Pascal
  • Gaubert Stéphane
  • Joswig Michael
  SIAM Journal on Applied Algebra and Geometry, Society for Industrial and Applied Mathematics, 2018, 2 (1), pp.140-178. We prove that primal-dual log-barrier interior point methods are not strongly polynomial, by constructing a family of linear programs with $3r+1$ inequalities in dimension $2r$ for which the number of iterations performed is in $\Omega(2^r)$. The total curvature of the central path of these linear programs is also exponential in $r$, disproving a continuous analogue of the Hirsch conjecture proposed by Deza, Terlaky and Zinchenko. Our method is to tropicalize the central path in linear programming. The tropical central path is the piecewise-linear limit of the central paths of parameterized families of classical linear programs viewed through logarithmic glasses. This allows us to provide combinatorial lower bounds for the number of iterations and the total curvature, in a general setting. (10.1137/17M1142132)
  DOI : 10.1137/17M1142132
• Hilbert and Thompson geometries isometric to infinite-dimensional Banach spaces
  
  • Walsh Cormac
  Annales de l'Institut Fourier, Association des Annales de l'Institut Fourier, 2018, 68 (5), pp.1831-1877. We study the horofunction boundaries of Hilbert and Thompson geome-tries, and of Banach spaces, in arbitrary dimension. By comparing the boundaries of these spaces, we show that the only Hilbert and Thompson geometries that are isometric to Banach spaces are the ones defined on the cone of positive continuous functions on a compact space.
• Derivation of an ornstein-uhlenbeck process for a massive particle in a rarified gas of particles
  
  • Bodineau Thierry
  • Gallagher Isabelle
  • Saint-Raymond Laure
  Annales de l'Institut Henri Poincaré (A). Physique Theorique, Birkhäuser, 2018, 19 (6). We consider the statistical motion of a convex rigid body in a gas of N smaller (spherical) atoms close to thermodynamic equilibrium. Because the rigid body is much bigger and heavier, it undergoes a lot of collisions leading to small deflections. We prove that its velocity is described, in a suitable limit, by an Ornstein-Uhlenbeck process. The strategy of proof relies on Lanford's arguments [17] together with the pruning procedure from [3] to reach diffusive times, much larger than the mean free time. Furthermore, we need to introduce a modified dynamics to avoid pathological collisions of atoms with the rigid body: these collisions, due to the geometry of the rigid body, require developing a new type of trajectory analysis. (10.1007/s00023-018-0674-6)
  DOI : 10.1007/s00023-018-0674-6
• Optimization of dispersive coefficients in the homogenization of the wave equation in periodic structures
  
  • Allaire Grégoire
  • Yamada T
  Numerische Mathematik, Springer Verlag, 2018, 140 (2), pp.265-326. We study dispersive effects of wave propagation in periodic media, which can be modelled by adding a fourth-order term in the homogenized equation. The corresponding fourth-order dispersive tensor is called Burnett tensor and we numerically optimize its values in order to minimize or maximize dispersion. More precisely, we consider the case of a two-phase composite medium with an 8-fold symmetry assumption of the periodicity cell in two space dimensions. We obtain upper and lower bound for the dispersive properties, along with optimal microgeometries.
• Study of new rare event simulation schemes and their application to extreme scenario generation
  
  • Agarwal Ankush
  • de Marco Stefano
  • Gobet Emmanuel
  • Liu Gang
  Mathematics and Computers in Simulation, Elsevier, 2018, 143, pp.89-98. This is a companion paper based on our previous work [ADGL15] on rare event simulation methods. In this paper, we provide an alternative proof for the ergodicity of shaking transformation in the Gaussian case and propose two variants of the existing methods with comparisons of numerical performance. In numerical tests, we also illustrate the idea of extreme scenario generation based on the convergence of marginal distributions of the underlying Markov chains and show the impact of the discretization of continuous time models on rare event probability estimation. (10.1016/j.matcom.2017.05.004)
  DOI : 10.1016/j.matcom.2017.05.004